And the first report was published by Mueller, a Norwegian physician in 1938. And they noticed an association of xanthomata, high cholesterol, and myocardial infarction. The first reports of FH interestingly came from dermatologists in the early part of 1930s. Her lipoprotein(a) was significantly elevated at 190 milligrams per dL. Her lipid profile is shown here with a total cholesterol of 338 and LDL cholesterol of 285, an HDL of 31, and a triglyceride level of 114 milligrams per dL. And her son later turned out to have high LDL cholesterol of 271 milligrams per dL. When we take a family history, we note that her mother died at age 50 of coronary heart disease. And on physical examination, she has the stigmata that are characteristic of familial hypercholesterolemia, including tendons xanthomata, particularly near the Achilles tendon, as well as arcus senilis, as seen here in this picture. This is a 35-year-old woman, who presents with ST elevation anterior myocardial infarction. Let's start with this case, which illustrates the dramatic and often unexpected presentations that can be manifest with FH. I'll describe the presentation of clinical criteria and the associated ASCVD risk, the burden of FH in the community, the merit of cascade screening, and then how we can manage these patients with drugs. I'll be first starting with the historical perspective and describe the genetic basis of this disease. Today, I'm going to give an update on familial hypercholesterolemia, which is a relatively common Mendelian disorder that is associated with a high risk of adverse cardiovascular events. And I'm a professor of medicine in the Department of Cardiovascular Disease, and also a consultant in the department. IFTIKHAR KULLO: Hello, my name Iftikhar Kullo. Presentation, clinical criteria and ASCVD risk (6:36). ![]() Historical perspective and genetic basis (0:58).Treatment for familial hypercholesterolemia includes drug therapy, and lifestyle modifications such as diet, physical activity and smoking cessation. Cascade screening also is important to identify additional family members who may carry this gene, as early treatment can be beneficial. Once a diagnosis has been established, additional testing including echocardiography, stress testing and lipoprotein (a) levels should be considered. Peoplewith familial hypercholesterolemia often present with atherosclerotic cardiovascular disease (ASCVD), xanthoma, arcus senilis and aortic stenosis. ![]() Familial hypercholesterolemia is also associated with a high risk of adverse cardiovascular events. For more information on familial hypercholesterolemia or to request an appointment, visit here.įamilial hypercholesterolemia is a common disorder that affects the way the body processes cholesterol. Kullo, M.D., discusses familial hypercholesterolemia.
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![]() Pound them thin (about ½ inch) for quick and even cooking. (2)Place them between sheets of parchment paper or plastic wrap. You can cut them into smaller cutlets if the pieces are too big. (1)Butterfly 2 pounds of chicken breasts by slicing them horizontally in half. Dry white wine: If you can't cook with alcohol, substitute with water or stock/broth.The smaller ones are called "nonpareils" and have a more delicate texture and flavor, while the bigger ones are more acidic. Capers: These green flower buds are salty and tangy.FInally, this promotion is in no way sponsored, endorsed or administered by, or associated with Facebook, Instagram, Pinterest, Twitter or any other social channel mentioned in the #LemonWeek posts or entry.Ingredients you’ll need Salt and pepper are not in the picture. In addition, void where prohibited by law. In addition, Bloggers hosting this giveaway and their immediate family members in their household cannot enter or win the giveaway. The #LemonWeek bloggers are not responsible for the fulfillment or delivery of the prize packages. Two (2) winners will be selected and sent prize packages directly from the giveaway sponsors. In addition, the number of entries received determines the odds of winning. Also, by entering you give the right to use your name and likeness. Moreover, all entries for the winner will be checked and verified. Of course, this giveaway is open to anyone 18 years or older in the United States. Enter to win a prize pack from Rodelle or La Tourangelle that include baking and cooking ingredients. Terms and conditions: This #LemonWeek is sponsored by Rodelle and La Tourangelle which starts and ends at 11:59pm ET. 2 count Gourmet Madagascar Vanilla Beans.Tried this recipe? Let us know how it was! Don’t Forget to Pin and Save the Recipe!Ĭheck out the amazing prizes you can win in our #LemonWeek Giveaway! Prize #1: Rodelle Prize Pack In addition, Grilled Mojito Chicken is a simple Cubano style of grilled chicken that makes an easy and flavorful warm weather meal. Or Grilled souvlaki chicken on a Greek type salad with pita croutons and Gyro-style tzatziki dressing. Then, Spiced shish tawook chicken, first marinated, then grilled, put the magic into a pita bread. Next, Indian spiced grilled chicken breast with exotic curry grilled corn makes for a spicy and healthy barbecue. Tandoori Chicken Tikka with Masala Grilled Corn You Might Also Like: Grilled Chicken Pinchitosįirst up, Grilled Chicken Pinchitos, or little skewers, are an Uruguayan delight of marinated chicken kebabs grilled and served with chimichurri dip. In any case, everyone will enjoy this with the usual cookout sides. Serving this on grilled French bread for sandwiches is another possible option. Or a simple garlic pasta made with vermicelli or angel-hair. I served this with the asparagus I made on Monday. However, this chicken is cooked outdoors for the extra grill flavor and slight smokiness. My recipe today is a take on the classic Italian chicken recipe. Today’s Recipe: Grilled Chicken Piccata.Dragonfruit Lemonade by Magical Ingredients.Oven Baked Lemon Pepper Chicken and Gnocchi by Jonesin’ For A Taste.Lemon Meringue Cheesecake by The Redhead Baker.Grilled Lemon Herb Flatbread by That Recipe.Lemon Sour Cream Pound Cake by Home Cooked Harvest.Ina Garten’s Lemon Chicken by Jen Around The World.Lemon Poppy Seed Cake by Kathryn’s Kitchen Blog.Lemon Crumb Muffins with Lemon Glaze by An Affair From The Heart.Rosemary Watermelon Lemonade by The Spiffy Cookie.Lemony Shrimp Pasta by A Day In The Life On The Farm.Italian Lemon Ricotta Cake by The Fresh Cooky.Homemade Lemon Cake by Simply Inspired Meals.Lemon Poppy Seed Thumb Print Cookies by Cheese Curd In Paradise.Meyer Lemon Vanilla Shortbread Cookies by Karen’s Kitchen Stories.Lemon Tarragon Salmon by Art Of Natural Living.Gluten Free Lemon Bars by Hezzi-D’s Books and Cooks. ![]() Creamy Lemon Smoothie Recipe by Blogghetti.Grilled Chicken Piccata by Palatable Pastime.Lemon Blueberry Cookies by Best Cookie Recipes.Lemon Poppy Seed Sweet Rolls by Fresh April Flours.We will bring you recipes from appetizers to drinks to entrées and desserts! Friday #LemonWeek Recipes Come join me and my fellow Lemon Week bloggers. These may have helped in the creation of my recipes. I may have received product samples from these sponsors. This week is sponsored by Rodelle and La Tourangelle. Welcome to #LemonWeek 2022 hosted by Lynn from Fresh April Flours and Rebecca from Devour Dinner. The giveaway is still going on so be sure you signed up. Grilled Chicken Piccata is my recipe of the day for my last offering in Lemon Week. Grilled Chicken Piccata By Sue Lau | Palatable Pastime Jump to Recipe Grilled chicken piccata adds outdoor cooked flavor to tender chicken with a lemony, caper and white wine sauce. Then, on top (usually right in the middle for effect) she pours the espresso, crema and all. This means that after the barista's finished steaming and foaming the milk, she'll gently pour it into your cup or glass. Instead of adding the espresso first, it's added last. Actually the same amount as a regular latte, but there's a twist. A latte macchiato is also milk-heavy, but the espresso is added lastĪs for a latte macchiato, it's got a lot of milk as well. ![]() The way you incorporate the milk dictates what the latte art will look like. You add in the espresso shot first (usually a double shot), then about 6 times more steamed and frothed milk, in a fluid motion. It's usually a large drink, reaching anywhere between 8 to 16 oz/236 to 470 ml, depending on where you get it from. There's steamed milk, microfoam, and regular milk foam in a latte. The milk is a lot, but mostly by volume rather than by weight. ![]() The name itself means 'milk' in Italian, so this should tip you off if you speak any Latin language. Starting with the latte, because this is one of the most common espresso-based drinks out there, along with cappuccino. A latte is a milk -heavy drink, a shot of espresso at the bottom If you're getting them to-go, then your only chance is to watch the barista. Depending on where you're getting them from, you might even be able to look at the different layers through the glass. Knowing what each of these drinks looks like will spare you a lot of trouble. What a latte, latte macchiato, and macchiato look like
![]() This article contains charart linearts made by seyriix for public use on the wiki by all members: Anyone may use these linearts to create visual references of their characters for their pages! Please be sure to thoroughly read the rules before using :) If you'd like to do so, please contact seyriix via any of their socials and wait for written permission to be given before going forward with anything. Heavily referencing or tracing the art provided here (for personal projects or otherwise) isn't permitted without the artist's permission.Redistributing these linearts, or the chararts made using them, for use on the blockchain or for AI-related software is strictly forbiddenn.Adjusting the lineart to better suit your character's description (i.e, removing a limb, adding nicks in an ear, etc.) is completely allowed, however!.If your art program doesn't support antialiasing, please instead use the pixel variations. This includes tracing the lineart, especially if you violate the second rule by doing so.Please do not modify the lineart to the point that it is unrecognisable as the original artist's work.Using these linearts as general bases (e.g, to create scenes with your characters, use on reference sheets, book covers, etc.) is not allowed.(i.e, you don't have to zoom in to make out the words) as long as it is still clear and visible to the naked eye. You are permitted to move the watermark to a different location etc.Removal or modification (to the point of unreadability) of the watermarks is prohibited, with no exceptions.Using a charart as your profile picture (or for something similar) on any platform is prohibited.Sharing them on Discord servers, whether private or public, is allowed as long as sufficient credit is supplied.Using or uploading the following linearts (and any subsequent chararts created with them, including your own) on different platforms, such as another wiki or website, is strictly forbidden. ![]() Or well, played, before the band switched vocalist and released the terrible album “Show Your Colours”. ![]() AmoralĪmoral plays a catchy take on progressive death metal. The band may sound a bit silly at times, but the music is insanely intense, abrupt and chaotic. CryptopsyĬryptopsy’s first two albums are righteously counted as classics in both brutal and technical death metal. Personally, I’m not that crazy about the super-ambitious newer material. Poland is filled with quality death metal, and Lost Soul is certainly one of the best. Sadly, the reincarnation of Kaamos has only released one EP, but it’s a damn good slab of old school Swedish death metal. Let’s begin the top 50 with a hidden gem – Sweden’s The Curse. If you dig the song, please stream/download our music from Bandcamp and follow us on Facebook. This is Desolator, old school death metal for fans of Immolation, Morbid Angel, Bloodbath and more. You’re here to check out death metal bands, after all? Well, I’m in one – and one of the purposes of this epic-size content is to make you listen to it. Pure melodeath bands (In Flames, Dark Tranquillity etc.).Riffs, energy, power and all the other obscure adjectives we associate with quality death metal.But I bet it’s going to be an entertaining read, and hopefully you will find some underrated death metal bands you didn’t know about. Some readers will be triggered, internet metal style. These are my personal favorites, some cult bands will most certainly be ranked below lesser-known ones. As a part of my recent full genre guide to death metal, I wanted to make an ultimate list of the best death metal bands. When Chuck Norris vetoed the idea (Norris didn't seem much of a fan of Winner's he once condemned the Death Wish movie's violent excess as being 'too negative' and, let's face it, Winner would have loved to dramatise the events referred to in that exchange I quoted at the top of this page) he brought in his brother, Aaron, to direct instead. Obviously with Golan and Globus bitterly estranged, Cannon would not consider Golan's return to the director's chair here, but further proof that Globus wanted to draw on the hits he had enjoyed with his cousin lies in the fact that the film was originally given to Michael Winner to direct. This ill-advised sequel, with its tale of its special forces hero seeking revenge against a seemingly untouchable and ruthless South American drug baron for the murder of his friends, feels like it was heavily influenced by the previous year's Bond film Licence to Kill. The continuity from the original may not be there but I'm glad they didn't just try and pass Ryan off as Marvin's character, because this would have been a huge disservice to the solid work he had done in The Delta Force. Ryan appears as his superior officer, General Taylor, in what is essentially the Lee Marvin role - but the character is written largely for comic relief (he gets to utter that ridiculous dialogue I quoted at the start of this review) and played as such with Ryan on scenery chewing form. With the demise of Marvin this is much more of a one man show for Chuck Norris, who returns to the role of Scott McCoy, now promoted to Colonel. Understandably they needed a hit that could pull audiences in, something familiar, and so the plans for a sequel were dusted off and it was finally put into production.though I really wish that it hadn't been.Ĭriticism of this sequel bearing little relation to the original is not unfounded. The professional split of Golan and Globus in 1989 saw Cannon - now led by Yoram Globus - desperate to prove that it was business as usual. ![]() Plans for a sequel to The Delta Force, the Menahem Golan directed Cannon film starring Chuck Norris and Lee Marvin, had first been mooted upon the film's release in 1986, but Marvin's death in 1987 had effectively put such plans on ice. I wouldn't mention any of this when you meet her, she's probably still a little touchy about it." - Genuine exchange in this film! " Cota killed her husband in front of her, then he killed her baby and used the corpse to smuggle cocaine, then he raped her. They relocate to Mars, but find the Soviets already there. The American campaign starts on the Moon, but the NSDF is forced off after the destruction of their main base. ![]() Gameplay is divided up into two campaigns one following the American National Space Defense Force (NSDF), the other with the Soviet Cosmos Colonist Army (CCA, also referred to as the Communist Cosmonaut Army in early game manuals). Both nations deploy into space and are fighting across the Solar System to control other deposits of the bio-metal. Both sides have used scraps of extraterrestrial "bio-metal", which have fallen to Earth as meteors, to build vehicles with amazing properties such as hover capability. A player can select a game to join and then connect to the host's computer.īattlezone is set during the turn of the 1970s with an alternative history plot, in which the Space Race is used to cover up the deployment of the United States and Soviet militaries into space. Online gaming used to be available at Activision's servers through Anet, a peer-to-peer networking system which features a chat lobby and a list of games in progress. When a sniper is killed, he (depending on map) will spawn at his original spawn point, or another spawn point on the map. Sniper game play consists of two or more players participating against each other in a "Deathmatch" style face off with their rifles. The game ends for each player as the player quit the game and only for the player quitting the game. Once destroyed, the pilot is ejected and floats back to the ground with the user's vehicle being respawned for continued play. In DeathMatch two or more players battle until the opposing vehicle is destroyed. The Strategy game ends when the opposing force lives are reduced to zero. Strategy offers the same type of control as in the single-player game. Strategy involves two or more players who compete in either as a player vs player, or playing in teams against one another, skirmishing for scrap collection and eventual map domination. Multiplayer īattlezone has a multiplayer feature that consists of three modes: Strategy, DeathMatch and Sniper. When a ship is destroyed, the pilot ejects and thus becomes vulnerable to being killed, but can escape by boarding any friendly vehicle. Players can acquire bio-metal scrap by either finding it or salvaging it from a destroyed enemy unit. Starting with a bio-metal recycler (the most basic construction unit), the player constructs vehicles to scavenge scraps of bio-metal, build base defenses, and construct new base vehicles capable of building more advanced structures and vehicles. Building and directing units is done via interface either by selecting onscreen object with the mouse or by using number keys on keyboard. The primary resource in Battlezone is bio-metal scrap which is used to produce new units and construct new buildings. A sequel, Battlezone II: Combat Commander, was released in 1999. In 2016, a remastered version titled Battlezone 98 Redux was released developed by Big Boat Interactive and published by Rebellion Developments. In 2000, a Nintendo 64 port was released under the name Battlezone: Rise of the Black Dogs. ![]() Two expansion packs were released in 1998, Battlegrounds and The Red Odyssey. In Battlezone the player is controlling everything on the battlefield from the first person view. Activision remade it into a hybrid of a tank simulation game, a first-person shooter and a real-time strategy game. Aside from the name and presence of tanks, this game bears little resemblance to the original arcade game of the same name. It was released for Microsoft Windows in 1998. Battlezone is a first-person shooter real-time strategy video game, developed and published by Activision. Outperforms other strong baseline MDS models under various evaluation metrics. OurĮxperimental results show that PeerSum is a challenging dataset, and Rammer Veusz add legend software Veusz add legend professional Veusz add. Metadata features in addition to the standard text generation objective. The hierarchical relationships and a multi-task objective that predicts several Generator), a meta-review generation model that uses sparse attention based on We additionally present Rammer (Relationship-aware Multi-task Meta-review Into MDS systems through attention manipulation on pre-trained language models, There is a scarcity of research that incorporates hierarchical relationships Hierarchical structure with cross-references and often feature conflicts. One can do something like AddX(1),MulY(2),Thin(4) I'm also thinking about how to hand plotting multiple datasets at once in a single plotter. They can transform both x and y (plus labels, colours and sizes). These source documents have rich inter-document relationships of an explicit This avoids creating one-off linked datasets and makes it easy to apply to lots of datasets. ![]() More to the point, I am having an issue using 'Filter: Expression' with Date type Data. I am also very impressed by how fast the package is evolving to meet the varied needs of the users. ![]() Generating meta-reviews of scientific papers, where the meta-reviews are highlyĪbstractive and genuine summaries of reviews and corresponding discussions. First of all, Veusz is an awesome plotting package, it's a great environment to work in and is very intuitive to use. ToĮnhance the capabilities of MDS systems we present PeerSum, a novel dataset for With explicit inter-document relationships that a summary must capture. Human-generated and genuine (i.e., not synthetic) summaries or source documents Download a PDF of the paper titled Towards Summarizing Multiple Documents with Hierarchical Relationships, by Miao Li and 2 other authors Download PDF Abstract: Most existing multi-document summarization (MDS) datasets lack Veuszis a plotting and graphing solution that enables you to manipulate your data sets in a well-organized graphical user interface and produce high-quality graphic depictions that can easily be. ![]() The mayor of one town said he was tired of people walking their dogs many times a day. Some mayors in Italy are posting angry messages on social media. ![]() Three-quarters of the world is in lockdown as countries try to contain the virus. Over 100,000 people in Italy have been fined for being on the streets without a good reason. ![]() There are many videos online of mayors going into the streets to order people to stay at home. The whole country is under lockdown but not everyone is following the rules. There have also been 8,215 deaths, the most of any country in the world. The country has reported over 80,000 cases of infections. It is one of the countries worst affected by the COVID-19 coronavirus. Please contact us for subscription options.Mayors across Italy are taking direct action to make sure people follow lockdown rules. The coronavirus attacks the respiratory tract with the potential to cause pneumonia and death.ĭespite its severity, most people experience mild symptoms and recover, but the elderly and those with pre-existing conditions are particularly vulnerable to the virus.Īnadolu Agency website contains only a portion of the news stories offered to subscribers in the AA News Broadcasting System (HAS), and in summarized form. ![]() The global death toll from the virus has hit 46,252 with 921,924 confirmed cases and 192,964 recoveries, according to U.S.-based Johns Hopkins University. To curb the rising risk of social turmoil, the cabinet is mulling an unprecedented emergency handout focusing on workers who were employed in Italy’s large underground economy and lost their jobs due to the lockdown.Ĭonte is also weighing the risk of relaxing the quarantine rules too soon against the huge economic fallout from the strict lockdown, which is expected to push the country’s already fragile economy into a dangerous recession.Īfter first appearing in the Chinese city of Wuhan in December, the virus, officially known as COVID-19, has spread to at least 176 countries and regions. The quarantine extension was widely expected, but the government faces growing fears of social unrest, especially in the poorer southern regions. However, he warned that the “battle is still very long.” “The data shows we are on the right path and that our drastic decisions are bearing fruit." "We must not view the first positive signs as an all-clear signal,” he said. Health Minister Roberto Speranza earlier in the day had already informed parliament that the government was planning to extend the nationwide quarantine. “We cannot plan an easing of the lockdown yet,” Prime Minister Giuseppe Conte said in a televised press conference Wednesday evening as he officially announced the extension of the lockdown to April 13.Ĭonte stopped short of providing a precise timing for when the lockdown will be lifted. The number of fatalities and new cases being reported are lower than figures seen over the past few weeks, however, supporting experts’ expectations that the contagion’s peak may be approaching.Īctive cases were up 3.8% from Tuesday, reaching 80,572, while the number of recovered patients rose to 16,847. The country reported 727 more deaths from the coronavirus compared with 837 a day before, bringing the total number of victims to 13,155, still the highest globally. Italy on Wednesday extended its stringent lockdown measures against the novel coronavirus for another two weeks as the death rate slowed. Nor did Republicans in Congress seize the reins when Trump came into office. Trump made none of that happen, aside from a few miles of expensive fence. Recall that Trump’s 2016 campaign was full of punchy lines: balancing the budget, repealing the Affordable Care Act, replacing it with a forever-TBD universal health plan, reshoring manufacturing, ending the trade deficit, building a beautiful border wall, making America great again. Norm Ornstein: I’ve witnessed the decline of the Republican Party And understanding how Republicans moved past policy requires looking not just at the negative space they left behind, but the positive space they have chosen to fill. The answer lies with the party as well as the president this development is due to decades-long demographic, cultural, and political trends, not just the makeup of the Trump administration. T his summer, I asked politicians, think-tank staffers, electoral consultants, political scientists, and pollsters why the Republican Party has felt so small, so devoid of vanward ideas to help Americans. It is also a sign that American democracy is in peril. This is not just proof that a man as interested in his own image as he is uninterested in briefing books should not be president. With the planet burning, the virus killing, the economy collapsing, and millions of Americans preparing to vote, the country’s leading political cabal has moved into a queasy post-policy space: Its aperture has narrowed to just a few issues its desire to try to pass major, proactive legislation has withered. (Put differently: It no-platformed itself.) And Republican leadership has gone dark on a huge swath of issues: balancing the budget, reforming entitlement programs, tackling climate change, improving public education, reducing student-loan debt, and ameliorating racial inequalities-as well as getting the country through the pandemic and out of the recession. Breaking with precedent, the party decided against producing an original platform for the 2020 convention. The GOP in general is remarkably quiet on how it would govern and what it seeks to accomplish in the coming years. Quinta Jurecic and Benjamin Wittes: Trump is campaigning on a platform of abject failure “Partner with Other Nations to Clean Up our Planet’s Oceans,” “Build the World’s Greatest Infrastructure System”: These are not plans so much as slogans, albeit ones that aren’t particularly catchy. There’s just a list of bullet points that the campaign put out on the eve of the convention. It contains no detailed forward-facing policy section, no vision of how to recover from the pandemic recession, no projection of a post-coronavirus future. It offers a threadbare recounting of his supposed accomplishments from his first term and a selection of festive collectibles. Trump campaign’s website provides no clearer message. You don’t have to drop bombs on everybody. An idiot like Bolton, all he wanted to do is drop bombs on everybody. … Now I know everybody, and I have great people in the administration. All of a sudden, I’m president of the United States. I’ve always said that, but the word experience is a very important word. I always say talent is more important than experience. The commander in chief’s answer: “You know, the word experience is still good. In June, the Fox News host Sean Hannity asked Trump to name his top-priority agenda items for his second term at a town hall held in Green Bay, Wisconsin. ![]() ![]() W hat does the Republican Party want? Although Donald Trump’s reelection campaign has shifted into full, strange force with an empty 2020 convention, it is a hard question to answer. |
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